Hermaphrodite with Mosaic
نویسندگان
چکیده
SIR,-In a recent review de Grouchy 1 compiles the following karyotypes described in true hermaphroditism: 46 XX, 46 XY, 46 XX/46 XY, 45 XO/46 XY, 46 XX/47 XXY, 46 XX/47 XXX, 46 XX/46 XY/45 XO, 46 XX/47 XXY/ 49 XXYYY, and 45 XO/46 X isoY/47 XY isoY. We have studied the chromosomes of a true hermaphrodite with a new mosaicism, 46 XX/46 XY/47 XXY, which might throw some light on the possible multiple pathogenesis of this clinical entity. A boy, aged 9 years, was seen in the endocrinological outpatient department of Hospital de San Pablo, Barcelona (Professor Vilaclara). He was an only child after 10 years of marriage. The family history was not contributory, and there
منابع مشابه
Child with True Hermaphroditism
True hermaphrodites possess both ovarian and testicular tissues which may be present in separate gonads or combined in an ovotestis. External and internal genitalia are ambiguous and variable, though a prominent penial structure is usual. Chromosome examination of true hermaphroditism has revealed an XX sex chromosome complement in the majority of cases, but the XY complement and different mosa...
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